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Jun 2023

Hypopituitarism : Causes, symptoms, diagnosis, treatment

Posted By Suborna Fermi Posted on Jun 24, 2023

The pituitary gland in our body is known as one of the majorly important organs that is responsible for generating multiple pituitary hormones. This kidney-bean sized important gland is situated at the base part of the brain and is considered as a part of the endocrine system of a human body. The pituitary hormones knowingly take part in so many kinds of crucial functionalities of a human body. Hypopituitarism is the name of the deficiency of one or multiple of these pituitary hormones. When the gland fails to produce sufficient amounts of hormones, this specific type of deficiency takes place. Hypopituitarism can be dangerous for you as that can leave many negative impacts on several routine functions of your body.

Although the signs and symptoms of this specific type of disorder may vary person to person, however, the signs and symptoms keep turning worse with time. It is necessary to know about the major signs and symptoms of hypopituitarism so that you can guess its presence in your body and take necessary actions at the right time. Some of the most mentionable signs and symptoms of hypopituitarism are mentioned here.

Major symptoms of hypopituitarism

The group of hormones produced by the pituitary gland are Growth hormone, Luteinizing hormone, follicle stimulating hormone, TSH, ACTH, ADH hormone, Prolactin etc. Take a glance at the primary symptoms of the deficiencies of some of these hormones.

Growth hormone deficiency symptoms are.

  • Fatigue
  • Lack of ambition
  • Social isolation
  • Changes in the composition of body fat
  • Muscle weakness

ADH deficiency symptoms are,

  • Electrolyte imbalance
  • Extreme thirst
  • Abnormally increased urination

ACTH deficiency symptoms are,

  • Low blood pressure
  • Extreme fatigue
  • Nausea
  • Abdominal pain
  • Vomiting
  • Frequent infections
  • Confusion

TSH deficiency symptoms are

  • Constipation
  • Fatigue
  • Dry skin
  • Weight gain
  • Increased sensitivity to cold

Follicle stimulating hormone deficiency symptoms in males are,

  • Undescended testicles
  • Micropenis
  • Fatigue
  • Infertility
  • Lower sex drive
  • Decreased facial hair
  • Decreased body hair
  • Erectile dysfunction

Follicle stimulating hormone deficiency symptoms in females are,

  • Fatigue
  • Infertility
  • Lower sex drive
  • Decreased public hair
  • Hot flashes
  • Irregular periods
  • Lower breast milk production

What causes hypopituitarism?

There are certain conditions that may lead to hypopituitarism. Hypopituitarism may show up in your body if

  • Some factor keeps pressurizing the pituitary gland or the Thalamus
  • Any sort of damage takes place in your pituitary gland

As mentioned before, there are certain health conditions that may lead to hypopituitarism. Take a glance at some of those factors.

Conditions and situations that may pressurize or damage pituitary or hypothalamus

  • Pituitary Adenomas
  • Lymphocytic hypophysitis
  • Hypothalamus or Pituitary sarcoidosis
  • Pituitary apoplexy
  • Brain tumors
  • Radiation Therapy
  • Surgery
  • Traumatic brain injury

Apart from all these, there are some rare health conditions that may cause hypopituitarism such as,

  • Bacterial meningitis
  • Hereditary Hemochromatosis
  • Certain kinds of genetic mutation

Fortunately, it’s not really a big deal these days to determine the presence of pituitary issues as so many modern test facilities can easily help you get your pituitary problems detected with complete accuracy. Certain tests will be performed on you to determine the presence of hypopituitarism in your body. Take a glance.

How to diagnose hypopituitarism?

  • Several blood tests will be performed on you for the purpose of measuring the levels of specific types of hormones in your blood.
  • A hormone stimulation test can be performed, in which medications are used for the purpose of stimulating the pituitary gland to release the hormone that needs to be tested.
  • MRI scans can also be used to determine the presence or absence of a pituitary tumor in your body.
  • Osmolality test for urine and blood is performed to determine the presence of ADH hormones in your body.
  • Brain CT scan can also be performed to detect the presence of a brain tumor.
  • An insulin tolerance test can also be performed for the purpose of detecting the deficiencies of ACTH hormone and growth hormone.

Although this is one of the most serious health conditions that can impact several functionalities of a human body, certain treatments are available that can help you get rid of hypopituitarism. However, if you have grown this disorder in your body, then most likely you have the potential to keep taking medications for the rest of your life.

Treatments for Hypopituitarism

  • Hormone replacement Therapy: A Hormone replacement Therapy can help to bring the reduced pituitary hormone levels back to normal level.
  • Radiation Therapy: There are certain kinds of pituitary Adenomas that can be treated through radiation therapy.
  • Adenoma removal surgery: You may also need to undergo a surgery for the purpose of getting the adenoma removed.

It’s necessary for each and every one of us to keep an eye on the pituitary gland functionalities through necessary tests so that we can take medical actions at the right time. There are certain risk factors of hypopituitarism that all of us must be aware of. There is a high chance for you to face hypopituitarism if

  • You are suffering from type 1 diabetes
  • You have a history of radiation therapy or cancer
  • You are suffering from sickle cell Anemia
  • You have a head or brain trauma

Apart from all these, lymphocytic hypophysitis is a specific type of condition that occurs in women who are pregnant, which can also lead to hypopituitarism. The wisest step to stay away from the potential risks that are associated with this condition is to get in touch with a doctor immediately or with a genuine and reliable pathology lab when the primary signs and symptoms of hypopituitarism start to show up.

Getting tested for hypopituitarism is easier now as so many advanced diagnostic centres are providing their services for a very reasonable price. Most of these diagnostic centres use advanced medical technologies as well as expert pathologists to detect the presence of diseases, so you can rely on their test report accuracy. Most of these diagnostic centres are now providing their services all over the country, so you can easily find one easily. Get in touch with one of these diagnostic centres today to get the presence of hypopituitarism detected in your body through a hormone test and stay out of many potential risks.